郭圣荣

教授|上海交通大学

概况

实验室简要介绍

代表成果

主要从事新型医药用高分子材料、药物输送系统的研究。在国内外学术期刊发表学术论文 120 多篇,主编专著 2 部、主译专著 1 部、参编多部,申请中国发明专利 18 多项(授权 8项)。

2011 中国药学会科学技术三等奖

2011 国家科学技术进步二等奖

2011 上海市自然科学三等奖


教学工作

教学课程

研究领域

新型药用辅料和新型药物制剂的开发

生物可降解高分子合成、性质表征及应用研究

用于药物和基因输送的微米 / 纳米,植入药剂

用于肿瘤治疗的药物缓释支架


大事记

重要事件

专利

  1. Guo S.-R., Lei L., Wang L.-Y., Wu W.-P., Hong W;A type of drug-releasing stent with internal supporting backbone;专利号:ZL 2009 1 0052143.6.
  2. Guo S.-R., Lei L., Hong W;A winged polymeric stent;专利号:ZL 2009 1 0052142.1.
  3. Guo S.-R., Guo Q.-H., Liu J., Wang Z.-M.;an anti-tumor drug particles-loaded stent;专利号:ZL2500 1 0111800.1.
  4. Guo S.-R., Guo Q.-H.;A preparation method for drug-loaded micro-/nano-sphere digestive tract stent;专利号:200510030444.0.
  5. Guo S.-R., Cheng L., Liu L., Tang X.-M.;Preparation method for a in situ chitosan hydrogel formulation;专利号:ZL2008 1 0041212.9.
  6. Guo S.-R., Lei L., Tang M.-F., Liu X;A dual drug-eluting stent featured with a bilateral drug release pattern and its preparation methods;专利号:CN 101810889 A. 2010.
  7. Guo S.-R., Hou J.-W., Lei L;A new synthetic method of biodegradable polycaprolactone for pharmaceutical application;专利号:CN 101831468 A. 2010.
  8. Guo S.-R., Chen W.-L., Guo D.-W., Shen Y.-Y.;A solid preparation based on highly hygroscopic excipients;专利号:201010501550.3.
  9. Guo S.-R., Cheng L.;A veterinary sustained praziquantel release implant and its preparation method;专利号:200910046684.8.
  10. Guo S.-R., Wang L., Tang T.-T., Peng Z.-X.;Synthesis of a chitosan quaternary ammonium salt.;专利号:200910308045.4.
  11. Peng Z.-X., Guo S.-R., Tang T.-T., Wang L.;A chitosan quaternary ammonium salt and its applications;专利号:200910195678.9.
  12. Guo S.-R., Cheng L., Guo Q.-H.;A matrix-type implant for killing canine parasites and its preparation method;专利号:CN101007171.
  13. Guo S.-R., Liu L.-B.;An S/O/W emulsion method for preparation of the 5-fluorouracil biodegradable polymer microsphere;专利号:200910049006.7.
  14. Guo S.-R., Guo Q.-H.;A polymer membrane-covered stent and its preparation method;专利号:CN1883718.
  15. Guo S.-R., Guo Q.-H.;A sustained drug release micro-/nano-sphere digestive tract stent;专利号:200510030443.6.
  16. Guo S.-R., Guo Q.-H.;A biodegradable drug release membrane-covered digestive tract stent;专利号:200510030452.5.
  17. Guo S.-R., Guo Q.-H., Wang Z.-M.;A matrix-type sustained drug release membrane-covered stent;专利号:200510030451.0.
  18. Xu Q.-F., Guo S.-R.;A dipyridamole/cyclodextrin derivative formulation and its preparation method;专利号:200510025929.0.

论文

  1. Physical characterization and osteogenic activity of the quaternized chitosan-loaded PMMA bone cement.Tan, H, Guo, S, Yang, S, Xu, X,Tang, T.Acta Biomaterialia.
  2. The use of quaternised chitosan-loaded PMMA to inhibit biofilm formation and downregulate the virulence-associated gene expression of antibiotic-resistant staphylococcus.Tan, H, Peng, Z, Li, Q, Xu, X, Guo, S,Tang, T.Biomaterials.
  3. Porous polycaprolactone/nanohydroxyapatite tissue engineering scaffolds fabricated by combining NaCl and PEG as co-porogens: Structure, property, and chondrocyte-scaffold interaction in vitro.Liu, L, Wang, Y, Guo, S, Wang, Z,Wang, W.Journal of Biomedical Materials Research - Part B Applied Biomaterials.
  4. PCL films incorporated with paclitaxel/5-fluorouracil: Effects of formulation and spacial architecture on drug release.Rong, HJ, Chen, WL, Guo, SR, Lei, L,Shen, YY.International Journal of Pharmaceutics.
  5. Application of poly(ethylene glycol)-b-poly(ε-caprolactone) copolymers with different poly(ethylene glycol) contents for the preparation of PEG-coated nanoparticles.Hou, JW, Qian, CY, Zhang, YT,Guo, SR.Journal of Biomedical Nanotechnology.

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